Figure 1. Peripheral blood smear demonstrating Auer rod within a promyelocyte.
| Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
| Journal website https://www.thejh.org |
Case Report
Volume 12, Number 2, April 2023, pages 100-104
Acute Promyelocytic Leukemia Treatment Masking Hepatic Tuberculosis: A Management Dilemma
Figures
Table
| Day | Significant event | SGOT (14 - 33 IU/L) | ALT (10 - 42 IU/L) | TB (0.2 - 1.0 mg/dL) | Alkaline phosphatase (40 - 129 IU/L) |
|---|---|---|---|---|---|
| ATO: arsenic trioxide; ATRA: all-trans retinoic acid; SGOT: serum glutamic-oxaloacetic transaminase; TB: total bilirubin. | |||||
| 1 | 33 | 26 | 1.5 | 91 | |
| 2 | ATRA started | 22 | 22 | 1.2 | 78 |
| 3 | Idarubicin started | 22 | 20 | 1.2 | 75 |
| 4 | 40 | 21 | 1.3 | 83 | |
| 9 | 66 | 102 | 1.9 | 112 | |
| 10 | ATO started | 61 | 89 | 1.2 | 121 |
| 11 | 70 | 91 | 1.3 | 122 | |
| 25 | 146 | 136 | 2.8 | 254 | |
| 26 | 172 | 146 | 3.6 | 259 | |
| 27 | Chemotherapy held | 192 | 167 | 3.8 | 261 |
| 30 | 232 | 231 | 3.4 | 380 | |
| 33 | 364 | 542 | 4.4 | 408 | |
| 34 | ATRA + 50% ATO dose restarted | 320 | 574 | 4.9 | 382 |
| 36 | 198 | 510 | 4.6 | 355 | |
| 38 | Hepatic TB diagnosed; chemotherapy held | 149 | 443 | 6.7 | 445 |
| 39 | TB treatment started | 153 | 403 | 5.0 | 414 |
| 43 | 244 | 521 | 4.1 | 487 | |
| 44 | ATRA resumed | 179 | 501 | 4.4 | 497 |
| 47 | 244 | 496 | 3.1 | 414 | |
| 49 | ATO restarted at 50% dose | 163 | 413 | 2.5 | 334 |
| 51 | 125 | 337 | 2.9 | 312 | |
| 56 | 83 | 164 | 2.4 | 405 | |
| 76 | ATO resumed at 100% | 58 | 57 | 2.3 | 441 |
| 156 | 31 | 62 | 0.8 | 81 | |