Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website https://www.thejh.org

Case Report

Volume 12, Number 2, April 2023, pages 87-91

A Meningioma Mimic and Distinct Subtype of Primary Central Nervous System Lymphoma: Primary Dural Lymphoma

Figures

Figure 1.
Figure 1. Pre-operative MRI scan. Dural-based homogeneously enhancing extra-axial mass along the left hemisphere with extension to the anterior interhemispheric falx and anterior right frontal lobe measuring 11 cm. There is significant mass effect and vasogenic edema. (a) Coronal section of the mass. (b) Sagittal section of the mass. (c) Transverse section of the mass. Post-operative MRI scan. Diffuse dural thickening through the left hemisphere, most notably along the left frontal lobe, reflecting postoperative changes of residual tumor. (d) Transverse section. (e) Sagittal section. (f) Coronal section. Post-chemotherapy MRI scan. Unchanged dural thickening and enhancement along the left hemisphere and anterior interhemispheric falx post-operatively. Some encephalomalacia in the left frontal lobe, but no new pathological enhancement seen. (g) T2 transverse section. (h) T1 axial section. MRI: magnetic resonance imaging.
Figure 2.
Figure 2. Resected tumor pathology stains. Hematoxylin and eosin stain of left frontal craniotomy tumor resection specimen shows focal residual germinal centers, partial plasmacytic differentiation and scattered large transformed cells. Low power × 40 (a). high power × 200 (b). Immunohistochemistry stain Ki67 proliferation index 10-20% (c). Stained CD45 diffusely positive (d).