Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
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Case Report

Volume 12, Number 6, December 2023, pages 272-276

Peripheral T-Cell Lymphoma in a Patient Previously Diagnosed With Sarcoidosis

Figures

Figure 1.
Figure 1. Cervical lymph node biopsy and bone marrow biopsy histology and immunohistochemistry confirming diagnosis of peripheral T-cell lymphoma, not otherwise specified (PTCL, NOS). (a)-(d) are cervical lymph node biopsy and (e)-(h) are bone marrow biopsy. (a) H&E of diagnostic lymph node at × 100. Clusters of epithelioid histiocytes have now been infiltrated by neoplastic lymphoid cells. (b) H&E of diagnostic lymph node at × 400. The arrows point to examples of large neoplastic T cells. (c) CD3 immunostain at × 100. (d) CD4 immunostain at × 400. The neoplastic T cells are CD4-positive/CD8-negative. (e) H&E of bone marrow at × 100. (f) H&E of bone marrow at × 400. (g) CD3 immunostain at × 100. (h) CD4 immunostain at × 400. H&E: hematoxylin and eosin.
Figure 2.
Figure 2. Outside lymph node biopsy from patient’s original diagnosis of sarcoidosis 2 years prior to admission. (a) H&E photograph of lymph node at × 100. (b) H&E of lymph node at × 400 with black arrows pointing to representative abnormal lymphocytes. (c) CD3 immunostain at × 100. (d) CD4 immunostain at × 400. H&E: hematoxylin and eosin.