Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc
Journal website https://www.thejh.org

Case Report

Volume 12, Number 6, December 2023, pages 287-293

Cryocrystalglobulinemia Leading to Multi-Organ Failure in Chronic Lymphocytic Leukemia Achieving Complete Renal Recovery

Figures

Figure 1.
Figure 1. Marked gangrene (red) of the right foot.
Figure 2.
Figure 2. Marked gangrene (red) of the left second and third digits.
Figure 3.
Figure 3. Light microscopy (hematoxylin and eosin stain): glomerulus with monocyte-rich, mesangial expansion and increase in matrix and cellularity consistent with membranoproliferative glomerulonephritis pattern of injury.
Figure 4.
Figure 4. Light microscopy (hematoxylin and eosin stain): immune type/hyaline microthrombi denoted with blue arrow.
Figure 5.
Figure 5. Electron microscopy showing subendothelial electron dense deposits denoted with blue arrow.
Figure 6.
Figure 6. Electron microscopy showing electron-dense deposits forming crystals at higher power denoted with blue arrows.