J Hematol

Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access

Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc

Journal website https://www.thejh.org

Original Article

Volume 13, Number 1-2, April 2024, pages 23-28

Natural Anticoagulant Protein Levels in Patients With Beta-Thalassemia Major: A Case-Control Study

Tables

**Table 1.** Coagulation Profile of Patients With β-Thalassemia Major in Comparison With Healthy Individuals
Parameters	Patients’ mean parameter	Healthy subjects’ mean parameter	P value	Normal range
PT: prothrombin time; APTT: activated partial thrombin time; PC: protein C; PS: protein S; AT: antithrombin; s: second.
PT (s)	19.5	14	0.001	10 - 14.5
APTT (s)	51.5	43	0.001	22 - 45
PC (%)	48.2 ± 65.4	97.1 ± 21.4	0.001	70 - 130
PS (%)	61.12 ± 21.1	72.2 ± 35.2	0.1	60 - 165
AT (%)	57.42 ± 13.6	81.79 ± 14.3	0.01	80 - 120

**Table 2.** Laboratory Characterizations of Patients With β-Thalassemia Major in Comparison With Healthy Individuals
Parameters	Patients’ mean parameter	Healthy subjects’ mean parameter	P value	Normal range
Hb: hemoglobin.
Hb (g/dL)	9.5 ± 3.1	13.5 ± 4.1	0.01	12.5 - 17.5
Iron (µg/dL)	745.95 ± 32.2	52.12 ± 4.13	0.0001	35 - 150
Ferritin (ng/mL)	2145.10 ± 74.3	92.1 ± 4.58	0.0001	30 - 200
Platelet (× 10⁹/L)	621 ± 4	245 ± 1	0.0001	150 - 400