Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
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Case Report

Volume 4, Number 4, December 2015, pages 242-245

Primary Bone Marrow B-Cell Lymphoma: Correlation of Results of Flow Cytometry and Morphological Findings


Figure 1.
Figure 1. Peripheral blood and bone marrow aspirate revealed large sized atypical lymphoma cells with indistinct nucleoli and basophilic cytoplasm (Leishman stain, × 200).
Figure 2.
Figure 2. Peripheral blood immunophenotyping: (A) SSC versus CD19 gating dot plot; (B) lambda chain restriction on CD19 positive cells; (C) positive for CD20 and negative for CD5; (D) negative for CD23; (E) negative for CD10 and positive for CD79b; (F) positive for CD 200 and CD38.
Figure 3.
Figure 3. Bone marrow biopsy revealed diffuse infiltration by atypical large lymphoma cells (H&E stain, × 200, × 400).
Figure 4.
Figure 4. Immunohistochemical stain of bone marrow biopsy: lymphoma cells are positive for CD20 and negative for CD3 (× 400, × 200).