| Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
| Journal website http://www.thejh.org |
Original Article
Volume 5, Number 3, September 2016, pages 94-98
Management of Arthropathy in Moderately Deficient Factor VII Patients: Results From Hospital Developed Treatment Protocol
Tables
| Period of rFVII administration | rFVII dose for patients with moderate factor VII deficiency (> 1 and < 10 IU/dL) |
|---|---|
| Pre-surgery | 15 - 25 μg/kg |
| On the surgery day (8 and 16 h, respectively) | 10 - 20 μg/kg |
| Rest of the days admitted in hospital | 15 - 20 μg/kg |
| Patient no. | Severity of disease | Surgical procedure | Treatment duration | No. of doses | Total dose of rFVII on surgical day (μg/kg) | Total dose of rFVII on subsequent days (μg/kg) | Dosing range (μg/kg) | Total amount of rFVII consumed (mg) |
|---|---|---|---|---|---|---|---|---|
| 1 | Moderate | Complete hip replacement | 13 | 29 | 54 | 288 | 12 - 30 | 22.23 |
| 2 | Moderate | Complete hip replacement | 14 | 31 | 40 | 280 | 10 - 20 | 23.04 |
| 3 | Moderate | Complete hip replacement | 13 | 29 | 35 | 260 | 10 - 15 | 22.42 |
| 4 | Moderate | Arthroscopy of shoulder | 10 | 16 | 45 | 195 | 15 | 16.8 |
| 5 | Moderate | Arthroscopy of ankle | 10 | 16 | 60 | 285 | 20 - 25 | 21.39 |
| 6 | Moderate | Arthroscopy of knee | 12 | 16 | 35 | 130 | 10 - 15 | 9.57 |