Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
Journal website http://www.thejh.org |
Original Article
Volume 5, Number 3, September 2016, pages 99-102
Prevalence of Hemoglobinopathies and Thalassemia Carriers in Women of Reproductive Age Group Especially the Prospective Mothers: A Single Center Study at West Bengal
Tables
Hemoglobinopathy | No. of patients |
---|---|
β-thalassemia trait | 50 |
Thalassemia trait HbE | 12 |
HbD Iran | 1 |
HbD Punjab | 1 |
Parameters | All (n = 1,083) | β-thalassemia trait (n = 50) | HbE carrier (n = 12) | Other hemoglobinopathy (n = 2) |
---|---|---|---|---|
Year of study | ||||
2010 | 102 (9.41%) | 8 (16%) | 4 (33.33%) | - |
2011 | 157 (14.49%) | 11 (22%) | - | - |
2012 | 197 (18.19%) | 7 (14%) | 1 (8.33%) | - |
2013 | 168 (15.51%) | 9 (18%) | 1 (8.33%) | 1 (50%) |
2014 | 253 (23.34%) | 10 (20%) | 4 (33.33%) | 1 (50%) |
2015 | 206 (19.02%) | 5 (10%) | 2 (16.66%) | - |
Age (years) | 21.6 ± 8.7 | 23.55 ± 9.10 | 24.7 ± 10.71 | 20.65 ± 8.4 |
Caste | ||||
Bengali | 714 (65.92%) | 26 (52%) | 8 (66.66%) | - |
Muslim | 184 (16.98%) | 10 (20%) | 2 (16.66%) | - |
Marwari | 153 (14.12%) | 8 (16%) | - | 1 (50%) |
Punjabi | 18 (1.66%) | 4 (8%) | - | - |
Others | 14 (1.29%) | 2 (4%) | 2 (16.66%) | 1 (50%) |
Diagnosis (n = 1,083) | No. of cases (%) | Hb (g/dL) | MCV (fL) | RBC (× 106/mm3) | MCHC (g/dL) | Hematocrit (%) | MCH (pg) |
---|---|---|---|---|---|---|---|
β-thalassemia trait | 50 (4.61) | 9.7 ± 1.9 | 62.4 ± 4.18 | 6.13 ± 1.01 | 28.2 ± 1.9 | 34.2 ± 4.8 | 22.4 ± 3.1 |
HbE carrier | 12 (1.10) | 10.8 ± 1.3 | 75.2 ± 4.9 | 4.27 ± 0.54 | 30.9 ± 2.1 | 37.7 ± 6.1 | 25.8 ± 2.7 |
Others carrier | 02 (0.18) | 11.6 ± 0.9 | 797 ± 5.0 | 4.78 ± 0.82 | 32.1 ± 0.9 | 38.1 ± 7.4 | 26.9 ± 2.9 |