Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
Journal website http://www.thejh.org |
Case Report
Volume 1, Number 2-3, June 2012, pages 70-73
Diabetes Insipidus as Presenting Manifestation of Waldenstrom’s Macroglobulinemia
Table
Pre-treatment | Fluid Restriction | Before DDAVP | After DDAVP | After 1st Plasma-pharesis | After 2nd Plasma-pharesis | After 4 cycles BDR | |
---|---|---|---|---|---|---|---|
DDAVP: vasopression; BDR: bendamustine, bortezomib, and rituximab. | |||||||
Serum osmolality (mOsm/kg H2O) | 330 | 323 | 332 | 321 | 314 | ||
Serum sodium (mmol/L) | 148 | 151 | 151 | 138 | 137 | ||
Serum Glucose (mg/dL) | 352 | 148 | 163 | 400 | 386 | ||
Urine osmolality (mOsm/kg H2O) | 188 | 159 | 222 | 234 | 330 | 863 | |
Urine sodium (mmol/L) | 45 | 37 | 54 | 61 | |||
IgM (mg/dL) | 2080 | 1560 | 287 | ||||
Viscosity (centiPoise) | > 20 | 2.7 | 1.7 | 1.6 |