Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
Journal website https://www.thejh.org |
Letter to the Editor
Volume 9, Number 3, September 2020, pages 93-95
Prevalence of Sickle Cell Trait and Rare Hemoglobin Variants in the Metropolitan Washington DC Area
Table
Hb type | Description | Total (%) |
---|---|---|
Hb: hemoglobin; SCD: sickle cell disease; SCA: sickle cell anemia. | ||
HbAA | Normal Hb | 3,182 (86.538%) |
HbAS | Sickle cell trait | 360 (9.791%) |
HbAC | HbC carrier | 98 (2.665%) |
HbSC | Hb S-C disease | 6 (0.163%) |
HbA HPFH | High HbF | 5 (0.135%) |
HbSS | SCD | 4 (0.109%) |
HbCC | Hb C disease | 3 (0.082%) |
HbA G-Philadelphia α-thalassemia | α-chain variant and α-globin gene deletion | 3 (0.082%) |
HbAE | HbE carrier | 2 (0.054%) |
HbAF | Normal HbA with high HbF | 2 (0.054%) |
HbA N-Baltimore | β-chain variant | 2 (0.054%) |
HbA β+ thalassemia | β-globin gene deletion carrier | 2 (0.054%) |
HbS β+ thalassemia | β-globin gene deletion and HbS | 2 (0.054%) |
HbSF | HbS with high HbF | 1 (0.027%) |
HbA2’ (A2 prime) | δ-chain variant | 1 (0.027%) |
Hb Hekinan | α-chain variant | 1 (0.027%) |
Hb Trenton | α-chain variant | 1 (0.027%) |
Hb A Hb Osu-Christiansborg | β-chain variant | 1 (0.027%) |
HbS α-thalassemia | SCA and α-globin gene deletion | 1 (0.027%) |
Total | 3,677 (100%) |