Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
Journal website https://www.thejh.org |
Case Report
Volume 10, Number 3, June 2021, pages 139-142
A Novel Case of Leflunomide-Induced Thrombotic Thrombocytopenic Purpura
Figure
Table
Reference range (our hospital) | 6 months prior to admission | 2 months prior to admission | Day 1 (other hospital) | Day 10 | Day 12 | Day 13 (our hospital) | Day 23 | Day 26 | Day 32 | Day 38 | Day 73 | Day 322 | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Platelets (103/µL) | 142 - 424 | 178 | 150 | 3 | 71 | 56 | 45 | 38 | 50 | 88 | 159 | 176 | 216 |
Hemoglobin (g/dL) | 14.1 - 18.1 | 12.4 | 11.6 | 7.3 | 9.3 | 8.9 | 8.4 | 8.4 | 8.2 | 8.4 | 8.6 | 10.7 | 10.7 |
White blood cells (103/µL) | 4.6 - 10.2 | 6.6 | 4.8 | 5.2 | 5.9 | 7.2 | 5.9 | 2.9 | 2.6 | 4.8 | 8.1 | 5.2 | 5.9 |
Lactate dehydrogenase (U/L) | 125 - 220 | 179 | - | 1,335 | 191 | 171 | 182 | 202 | 261 | 321 | 260 | 208 | 208 |
Total bilirubin (mg/dL) | 0.2 - 1.2 | 0.4 | 0.5 | 3 | 0.9 | 0.6 | 0.8 | 0.8 | 0.9 | 0.7 | 0.4 | 0.3 | 0.4 |
ADAMTS13 activity (%) | 68 - 163 | - | - | 5 | - | - | 82 | 86 | - | - | - | 82 | - |