Figure 1. Peripheral blood smear of our patient. Note multiple hypersegmented neutrophils (red arrow) and schistocytes (blue arrow). Additionally, this smear is significant for marked anisocytosis, poikilocytosis, macrocytosis and hypochromia.
| Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Hematol and Elmer Press Inc |
| Journal website https://www.thejh.org |
Case Report
Volume 10, Number 4, August 2021, pages 202-205
Severe Vitamin B12 Deficiency Mimicking Microangiopathic Hemolytic Anemia
Figure
Table
| Hgb (g/dL) | MCV (fL) | Platelets (× 103/μL) | RPI | LDH (U/dL) | Total bilirubin (mg/dL) | Unconjugated bilirubin (mg/dL) | Haptoglobin (mg/dL) | B12 (pg/mL) | MMA (nmol/L) | |
|---|---|---|---|---|---|---|---|---|---|---|
| Hgb: hemoglobin; MCV: mean corpuscular volume; RPI: reticulocyte production index; LDH: lactate dehydrogenase; MMA: methylmalonic acid. | ||||||||||
| Day 1 | 5.3 | 106.2 | 81 | 0.47 | > 4,000 | 1.5 | 1.2 | < 31 | < 60 | |
| Day 2 | 5.0 | 103.7 | 126 | 1.7 | 1.3 | |||||
| Day 3 | 8.0 | 94.2 | 83 | 2.2 | 1.8 | 3,460 | ||||
| Day 4 | 8.7 | 95.0 | 80 | 1.8 | 1.4 | |||||
| 2 weeks | 10.1 | 97.9 | 788 | 1.54 | 1,119 | 0.7 | 0.5 | 87 | 4555 | 136 |
| 3 months | 13.4 | 82.3 | 640 | 0.2 | 0.1 | |||||