Journal of Hematology, ISSN 1927-1212 print, 1927-1220 online, Open Access
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Case Report

Volume 11, Number 1, February 2022, pages 40-44

Ischemic Stroke and Bilateral Pulmonary Embolism in COVID-19: COVID-Associated Coagulopathy or Heparin-Induced Thrombocytopenia


Figure 1.
Figure 1. Platelets and D-dimer levels in relation to day of hospitalization. Blue line represents the trend of platelet count (× 103/µL) during inpatient hospitalization. Note that the patient presented with mild thrombocytopenia but levels remained consistently above 120 × 103/µL. The graph highlights the remarkable decrease in platelet count around hospital day 13 that led to diagnosis of HIT and appropriate management. Red line shows the trend of D-dimer levels (ng/mL) during hospitalization. Note that levels have peaked on hospital day 5 as well as other inflammatory markers consistent with impending cytokine storm and respiratory failure. Levels have markedly increased again around hospital days 10-11 in the setting of bilateral PE. HIT: heparin-induced thrombocytopenia; PE: pulmonary embolism.