Acquired Hemophilia Secondary to Rheumatoid Arthritis: Case Report and Literature Review

Orivaldo Alves Barbosa, Priscila Dourado Evangelista, Jose Gerardo Araujo Paiva, Tadeu Goncalves de Lima, Romano Bezerra Brasileiro, Ramiro Rolim Neto, Cibele Silveira Pinho, Max Victor Carioca Freitas

Abstract


Acquired hemophilia is a bleeding disorder caused by the development of autoantibodies against plasma coagulation factors, most frequently against the factor VIII, or type A. We report a case of a 69-year-old patient with rheumatoid arthritis for 6 years with ecchymoses, hematomas and macroscopic hematuria, diagnosed with acquired hemophilia A secondary to rheumatoid arthritis, treated with methylprednisolone, desmopressin, activated prothrombin complex concentrate and cyclophosphamide, with remission.




J Hematol. 2016;5(1):34-37
doi: http://dx.doi.org/10.14740/jh255w


Keywords


Bleeding; Rheumatoid arthritis; Acquired hemophilia

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