Journal of Hematology

Editor-in-Chief
Roberto Castelli, MD, PhD, Professor, Division of Internal Medicine, Department of Biomedical and Clinical Sciences, University of Milan, Italy Read more...

ISSN 1927-1212 print
ISSN 1927-1220 online
Frequency: Quarterly (Bimonthly from 2021)
Journal Access: Open Access
Indexed and covered by: Chemical Abstract (CA); Worldcat; Google; Google Scholar; JournalTOCs; PubMed Central; PubMed; Web of Science (Emerging Sources Citation Index-ESCI).
Journal archiving and digital preservation: Portico

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Highlights

Ofatumumab and Complement Replacement in Relapsed/Refractory Chronic Lymphocytic Leukemia
We conducted a phase 2 trial involving patients with relapsed/refractory chronic lymphocytic leukemia (CLL). Patients were treated with ofatumumab with fresh frozen plasma (FFP) used as a source of complement replacement.
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Spontaneous Remission in a Patient With Acute Myeloid Leukemia Leading to Undetectable Minimal Residual Disease
Although rare, spontaneous remission (SR) of acute myeloid leukemia (AML) has been reported in the literature, the underlying mechanisms driving remission remain unknown. However, it is most commonly associated with a preceding severe infection.
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Impact of Opioid Use in Hematological Malignancies: Clinical, Immunological and Concomitant Aspects
Opioid agents play a unique role in pain and symptom management for cancer patients. Research shows that opiate use, especially when associated with underlying cancer, has significant effects on hematological parameters.
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Outcomes of Reduced Frequency Dosing of Ibrutinib in Chronic Lymphocytic Leukemia Patients Following Complete or Partial Remission: A Pilot Study
Ibrutinib is a Bruton’s tyrosine kinase inhibitor that has shown to be a superior choice in the treatment of chronic lymphocytic leukemia (CLL) and a simple, oral alternative to other chemoimmunotherapies.
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Delayed Thrombotic Complications in a Thrombotic Thrombocytopenic Purpura Patient Treated With Caplacizumab
Caplacizumab has emerged as a promising new drug for the management of TTP. We report the case of a patient with idiopathic refractory TTP treated with caplacizumab who developed thrombotic complications upon discontinuation of treatment.
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Viewpoints

Featured

The Impact of Preoperative Intravenous Iron Therapy on Perioperative Outcomes in Cardiac Surgery: A Systematic Review
Anemia is common in cardiac surgery affecting 25-40% of patients and associated with increased blood transfusions, morbidity, mortality, and higher hospital costs. Higher rates of stroke, acute renal injury, and total number of adverse postoperative outcomes have also been reported to be associated with preoperative anemia. Read the Full Text

Reduce Mortality and Morbidity in Acute Myeloid Leukemia With Hyperleukocytosis With Early Admission in Intensive Care Unit: A Retrospective Analysis
Patients presenting with acute myeloid leukemia (AML) at diagnosis are at high risk of severe complications and death, particularly with high white blood cell (WBC) count. In this retrospective study, we evaluate interest of early and systematic support in the intensive care unit (ICU) for AML with hyperleukocytosis (AML-HL) at diagnosis. Read the Full Text

Image of the Issue

Molecular Genetic Analysis With Flow Cytometry Sorting Identifies Angioimmunoblastic T-Cell Lymphoma and Concomitant De Novo Myelodysplastic Syndrome Arising From the Same Hematopoietic Progenitor
A 75-year-old man with no prior history of cytotoxic therapy presented with increasing fatigue and shortness of breath. He was found to have a new onset of pancytopenia, and chest X-ray showed severe pneumonia. Additional radiology exam revealed pan-lobar pneumonia, pleural effusion, generalized lymphadenopathy and mild splenomegaly. Full Text

Current Issue

Vol. 9, No. 4, Dec 2020

Review

The Impact of Preoperative Intravenous Iron Therapy on Perioperative Outcomes in Cardiac Surgery: A Systematic Review	Abstract HTML PDF Suppl1
Kelly A. Tankard, Brian Park, Ethan Y. Brovman, Angela M. Bader, Richard D. Urman	97-108
doi: https://doi.org/10.14740/jh696

Original Article

Reduce Mortality and Morbidity in Acute Myeloid Leukemia With Hyperleukocytosis With Early Admission in Intensive Care Unit: A Retrospective Analysis	Abstract HTML PDF
Nathan Mottal, Nahema Issa, Pierre-Yves Dumas, Fabrice Camou, Mathieu Sauvezie, Francois-Xavier Gros, Titouan Cazaubiel, Gaelle Mourissoux, Harmony Leroy, Arnaud Pigneux, Olivier Guisset, Thibaut Leguay	109-115
doi: https://doi.org/10.14740/jh691

Prognostic Role of Lymphocyte/Monocyte Ratio in Chronic Lymphocytic Leukemia	Abstract HTML PDF
Osman Yokus, Esma Nur Saglam, Hasan Goze, Fettah Sametoglu, Istemi Serin	116-122
doi: https://doi.org/10.14740/jh730

Treatment-Related Mortality From Infectious Complications in an Acute Leukemia Clinic	Abstract HTML PDF
Jorge Torres-Flores, Ramiro Espinoza-Zamora, Jorge Garcia-Mendez, Eduardo Cervera-Ceballos, Alejandro Sosa-Espinoza, Nidia Zapata-Canto	123-131
doi: https://doi.org/10.14740/jh751

Case Report

Unraveling the Mystery of Gray Zone Lymphoma in Human Immunodeficiency Virus-Seropositive Patients: Two Cases	Abstract HTML PDF
Amith Ahluwalia, Leena Bondili, Julius Salamera, Michelle Cholankeril	132-136
doi: https://doi.org/10.14740/jh554

Unexpected Neurological Symptoms of Ruxolitinib: A Case Report	Abstract HTML PDF
Francesca Furia, Maria P. Canevini, Augusto B. Federici, Maria C. Carraro	137-139
doi: https://doi.org/10.14740/jh642

Molecular Genetic Analysis With Flow Cytometry Sorting Identifies Angioimmunoblastic T-Cell Lymphoma and Concomitant De Novo Myelodysplastic Syndrome Arising From the Same Hematopoietic Progenitor	Abstract HTML PDF
Ken Naganuma, Alexander Chan, Yanming Zhang, Natasha Lewis, Wenbin Xiao, Mikhail Roshal, Ahmet Dogan, Masahiro Kizaki, Caleb Ho, Mariko Yabe	140-146
doi: https://doi.org/10.14740/jh760

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Journal of Hematology