Journal of Hematology

Farhad Ravandi, MD, Professor
Janiece and Stephen A. Lasher Professor of Medicine
Chief, Section of Acute Myeloid Leukemia
Department of Leukemia
The University of Texas MD Anderson Cancer Center, Texas, USA  Read more...

ISSN 1927-1212 print | ISSN 1927-1220 online | Bimonthly | Open Access | Aims and Scope

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  • Efficacy of Frontline Chemotherapy for Extranodal Natural Killer/T-Cell Lymphoma: A Systematic Review and Network Meta-Analysis

    Treatment with non-anthracycline (ANT)-based chemotherapy has increased survival in patients with extranodal natural killer/T-cell lymphoma (ENKTCL). However, the relative efficacy of various drug combinations has been contentious.

  • Harnessing the Immune System: An Effective Way to Manage Diffuse Large B-Cell Lymphoma

    Diffuse large B-cell lymphoma (DLBCL) is a heterogenous hematological disorder with malignant potential controlled by immunological characteristics of the tumor microenvironment. Rapid breakthrough in the molecular pathways has made immunological approaches the main anchor in the management of DLBCL, with or without chemotherapeutic agents.

  • Incidence and Risk of Hematological Adverse Events Associated With Immune Checkpoint Inhibitors: A Systematic Literature Review and Meta-Analysis

    Immune checkpoint inhibitors (ICIs) have been a breakthrough in cancer therapy. ICI therapy is generally better tolerated than cytotoxic chemotherapy; however, hematological adverse events (AEs) have not been fully analyzed.

  • Mature Type T-Lymphoblastic Leukemia/Lymphoma Presenting With Isolated Central Nervous System Symptomatology in a Patient With Giant Cell Arteritis on Long-Term Steroid Treatment

    T-lymphoblastic leukemia/lymphoma (T-ALL/T-LBL) is a malignancy comprised of T-lymphoblasts that can present as one of four clinical subtypes (pro-T, pre-T, cortical T, and mature T).

  • Acute Myeloid Leukemia Following Myeloproliferative Neoplasms: A Review of What We Know, What We Do Not Know, and Emerging Treatment Strategies

    Acute myeloid leukemia (AML) arising from myeloproliferative neoplasms (MPNs) represents a small subtype of secondary AML (sAML). This entity is well known to be associated with poor responses to available treatment options and dismal outcomes.







Real-World Data of Crizanlizumab in Sickle Cell Disease: A Single-Center Analysis
Crizanlizumab was approved by the United States Food and Drug Administration agency in 2019 for decreasing vaso-occlusive events (VOEs) in sickle cell disease (SCD). Data regarding the use of crizanlizumab in the real-world setting are limited. Full Text

Local and Systemic Immunity During Five Vaccinations Against SARS-CoV-2 in Zanubrutinib-Treated Patients With Chronic Lymphocytic Leukemia
Patients with chronic lymphocytic leukemia (CLL) are vulnerable to coronavirus disease 2019 (COVID-19) and are at risk of inferior response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination, especially if treated with the first-generation Bruton’s tyrosine kinase inhibitor (BTKi) ibrutinib. Full Text

Key Clinical Image

Sickle Cell Trait: Is It Always Benign?
Sickle cell disease is a well-known homozygous inherited hemoglobinopathy that causes vaso-occlusive phenomena and chronic hemolysis. Vaso-occlusion results in sickle cell crisis and can eventually lead to complications involving multiple organ systems. However, the heterozygous counterpart, sickle cell trait (SCT) has less clinical significance as these patients are generally asymptomatic. Full Text

Current Issue


Vol. 12, No. 5, Oct 2023

Table of Contents

Original Article

The Impact of Renal Impairment in Multiple Myeloma Patients Undergoing Autologous Stem Cell Transplantation With Melphalan Conditioning Abstract HTML PDF
Sorana G. Ursu, Samantha Maples, Kiersten J. Williams, Gina Patrus, Yazan Samhouri, Salman Fazal, Prerna Mewawalla, Santhosh Sadashiv 201-207
Validation of the New MINI-CUBE for Clinic Determination of Erythrocyte Sedimentation Rate Abstract HTML PDF Suppl1
Flaminia Tomassetti, Martina Pelagalli, Eleonora Nicolai, Serena Sarubbi, Cinzia Calabrese, Alfredo Giovannelli, Silvia Codella, Gemma Viola, Daniela Diamanti, Renato Massoud, Sergio Bernardini, Massimo Pieri 208-214
Efficacy of Frontline Chemotherapy for Extranodal Natural Killer/T-Cell Lymphoma: A Systematic Review and Network Meta-Analysis Abstract HTML PDF Suppl1 Suppl2 Suppl3 Suppl4 Suppl5 Suppl6
Fei Luo, Jing Nan Wang, Xin Liu, Xin Wang, Shu Nan Qi, Ye Xiong Li 215-226

Case Report

A Rare Coexistence of Multiple Myeloma and Polycythemia Vera Abstract HTML PDF
Alexander Landsman, Priyanka Barua, Alida Podrumar 227-230
Cyclic Thrombocytopenia in the Setting of Intracranial Hemorrhage: A Diagnostic and Therapeutic Challenge Abstract HTML PDF
Ryan Sweeney, Maitreyee Rai, Harmeet Kharoud, Rama Bhagavatula, Robert Kaplan, Deep Shah 231-235
When Lymphoma Strikes the Pancreas: A Rare Presentation of Systemic Anaplastic Lymphoma Kinase-Negative Anaplastic Large Cell Lymphoma in a Human Immunodeficiency Virus-Positive Patient Abstract HTML PDF
Hehua Hannah Huang, Xin Qing 236-242

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Journal of Hematology, bimonthly, ISSN 1927-1212 (print), 1927-1220 (online), published by Elmer Press Inc.                            
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