Heterozygous Factor V Leiden R506Q Mutation Causing a Life-Threatening Bilateral Pulmonary Embolism in a Young Man With Influenza A Pneumonitis

Abdelkarim Waness, Ashraf Elghul

Abstract


Factor V Leiden (FVL) single R506Q mutation is an inherited familial condition that predisposes to increased risk of thrombophilia. This risk is lower in the heterozygous mutation form compared to the homozygous one. The pathologic clotting might occur at any age group and potentially in various sites of the body vasculature. We present a case of heterozygous form of FVL single R506Q mutation causing life-threatening bilateral pulmonary emboli in a previously healthy young male who suffered severe case of influenza A pneumonitis.




J Hematol. 2014;3(2):54-56
doi: http://dx.doi.org/10.14740/jh127w


Keywords


Factor V Leiden; Single R506Q mutation; Pulmonary emboli; Pleural effusion; Pericardial effusion; Influenza A; Pneumonitis

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