Treatment for Factor V Leiden, Stuck Between a Rock and a Hard Place: A Case Report and Review of Literature

Waqas Jehangir, Souad Enakuaa, Victoria Udezi, Nilma Malik, Shuvendu Sen, Abdalla Yousif, Mohammed A Islam


Factor V Leiden is a genetically inherited disorder which causes hypercoagulable state that accounts for 40-50% of cases of thrombophilia. The diagnosis of factor V Leiden thrombophilia is made either by using a coagulation screening test or by DNA analysis of F5, which encodes the factor V protein. Management of this disorder can be challenging due to the fact that the current treatment regimen can place the patient in a bleeding state with potential hazardous effects. We are reporting the case of a 49-year-old man who presented with shortness of breath diagnosed with multiple episodes of pulmonary embolisms, DVT and factor V Leiden deficiency treated with oral anticoagulants again presented with dizziness and upper GI bleed.

J Hematol. 2014;3(2):43-45


Factor V Leiden; Pulmonary embolism; Thrombophilia

Full Text: HTML PDF

Browse  Journals  


Journal of Clinical Medicine Research

Journal of Endocrinology and Metabolism

Journal of Clinical Gynecology and Obstetrics

World Journal of Oncology

Gastroenterology Research

Journal of Hematology

Journal of Medical Cases

Journal of Current Surgery

Clinical Infection and Immunity

Cardiology Research

World Journal of Nephrology and Urology

Cellular and Molecular Medicine Research

Journal of Neurology Research

International Journal of Clinical Pediatrics






Journal of Hematology, bimonthly, ISSN 1927-1212 (print), 1927-1220 (online), published by Elmer Press Inc.                            
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC BY-NC 4.0)

This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website:    editorial contact:
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

Disclaimer: The views and opinions expressed in the published articles are those of the authors and do not necessarily reflect the views or opinions of the editors and Elmer Press Inc. This website is provided for medical research and informational purposes only and does not constitute any medical advice or professional services. The information provided in this journal should not be used for diagnosis and treatment, those seeking medical advice should always consult with a licensed physician.