Myelodysplastic Syndrome and Polymyalgia Rheumatica Associated With Pernicious Anemia

Koji Otsuka, Takakazu Higuchi, Akihiro Nakajima, Ryosuke Koyamada, Chisun Min, Masato Okada, Sadamu Okada


An 83-year-old man who had been treated for pernicious anemia (PA) developed myelodysplastic syndrome (MDS) and polymyalgia rheumatica (PMR). While PA patients are at an increased risk of malignant tumors, association with MDS is rarely reported. PA patients are also associated with various autoimmune conditions; however, association with PMR has not been reported. Derangement in the immune system associated with PA and subsequent MDS was assumed to have contributed to the development of PMR.

J Hematol. 2015;4(2):181-183


Autoimmunity; Myelodysplastic syndrome; Pernicious anemia; Polymyalgia rheumatica

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