Cerebrovascular Disease as Initial Clinical Presentation in a Patient With Idiopathic Thrombotic Thrombocytopenic Purpura: A Case Report

Abstract

There are very few hematological emergencies that they are usually excluded from the list of differential diagnosis; nonetheless, if untreated, they can lead to devastating results. Thrombotic thrombocytopenic purpura (TTP) is a thrombotic microangiopathy with characteristic von Willebrand factor (vWF)-rich microthrombi affecting the arterioles and capillaries of multiple organs. It represents both a diagnostic and management challenge to clinicians. Timely recognition and institution of appropriate therapy are of paramount importance in optimizing outcome. Nevertheless, TTP may have an unpredictable behavior once is diagnosed because of its variable frequency of relapses and exacerbations.




doi:10.4021/jh102e