Diffuse Large B-Cell Lymphoma Presenting as an Endobronchial Mass: A Case Report and Review of Literature

Abstract

Diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype of non-Hodgkin lymphoma (NHL). DLBCL normally presents with nodal involvement in the neck or the abdomen. Extranodal extramedullary disease is seen in up to 40% of cases. However, endobronchial involvement is very rare. Here we describe a 77-year-old woman with a history of bronchial asthma presenting with cough and shortness of breath who was initially treated for exacerbation of asthma. Persistent symptoms lead to further evaluation including CT scan and bronchoscopy, resulting in the diagnosis of DLBCL in this woman presenting as an endobronchial lesion. This case demonstrates the importance of considering lymphoma as a differential diagnosis of an isolated endobronchial lesion.




J Hematol. 2016;5(3):106-109
doi: http://dx.doi.org/10.14740/jh283w