A Rare t(5;11)(q35;q13) Translocation in an Elderly Patient With Acute Myeloid Leukemia With Maturation: A Case Report

Masahiro Manabe, Yuuji Hagiwara, Reiko Asada, Dai Momose, Yasuyoshi Sugano, Ki-Ryang Koh

Abstract


The t(5;11)(q35;q13) reciprocal translocation is a rare chromosomal abnormality that can arise in myeloid neoplasms, mainly in children and younger adults. Here, we report a case of acute myeloid leukemia with maturation, involving an 85-year-old, in which the tumor cells harbored the t(5;11)(q35;q13) chromosomal abnormality. We also address the diagnostic and immunophenotypic characteristics of acute myeloid leukemia involving t(5;11)(q35;q13), along with a review of the literature.




J Hematol. 2018;7(2):79-82
doi: https://doi.org/10.14740/jh394w

Keywords


t(5; 11)(q35; q13); Acute myeloid leukemia with maturation; Elderly

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